GMPS Antibody

Novus Biologicals | Catalog # NBP3-29817

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

between 650 and 693

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GMPS Antibody

GMPS Antibody

Western Blot:[NBP3-29817]-

Western Blot:[NBP3-29817]-Detection of human GMP synthase by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa cells. Antibodies: Affinity purified rabbit anti-GMP synthase antibody used for WB at 0. 04 µg/ml and 1 µg/ml and used for IP at 3 µg/mg lysate. GMP synthase was also immunoprecipitated by rabbit anti-GMP synthase antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes and 10 seconds.

Applications for GMPS Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-buffered Saline 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: GMPS

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Alternate Names

EC 6.3.5.2, Glutamine amidotransferase, GMP synthase, GMP synthase [glutamine-hydrolyzing], GMP synthetase, guanine monphosphate synthetase, guanosine 5'-monophosphate synthase, MLL/GMPS fusion protein

Gene Symbol

GMPS

Additional GMPS Products

Product Documents for GMPS Antibody

Certificate of Analysis

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Product Specific Notices for GMPS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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