GNB3 Antibody (S01-9F3)

Novus Biologicals | Catalog # NBP3-15035

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-9F3 expressed in HEK293
View all GNB3 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human GNB3 (Uniprot#: P16520)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GNB3 Antibody (S01-9F3)

Western Blot: GNB3 Antibody (S01-9F3) [NBP3-15035]

Western Blot: GNB3 Antibody (S01-9F3) [NBP3-15035]

Western Blot: GNB3 Antibody (S01-9F3) [NBP3-15035] - Western blot detection of GNB3 in C6, Rat Brain, MCF7 cell lysates using GNB3 Rabbit mAb (1:1000 diluted). Predicted band size: 37KDa. Observed band size: 37KDa.

Applications for GNB3 Antibody (S01-9F3)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GNB3

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

Alternate Names

G protein, beta-3 subunit, GTP-binding regulatory protein beta-3 chain, guanine nucleotide binding protein (G protein), beta polypeptide 3, guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, hypertension associated protein, Transducin beta chain 3

Gene Symbol

GNB3

Additional GNB3 Products

Product Documents for GNB3 Antibody (S01-9F3)

Certificate of Analysis

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Product Specific Notices for GNB3 Antibody (S01-9F3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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