Gremlin 1 Antibody - BSA Free

Novus Biologicals | Catalog # NB100-56883

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Cited:

Immunohistochemistry-Paraffin, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

A synthetic peptide containing amino acids QPGSRNRGRGQGRGTA (52-67) of human CKTSF1B1 (NM_013372).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Gremlin 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Gremlin 1 Antibody [NB100-56883]

Immunohistochemistry-Paraffin: Gremlin 1 Antibody [NB100-56883]

Immunohistochemistry-Paraffin: Gremlin 1 Antibody [NB100-56883] - Detection of Gremlin in human colon cancer tissue using antibody at 5 ug/ml.

Applications for Gremlin 1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:1000

Immunohistochemistry-Frozen

reported in scientific literature (Namkoong et al (2006))

Immunohistochemistry-Paraffin

2.5-10 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Gremlin

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

Alternate Names

DAND2, DRM, GREM1

Entrez Gene IDs

26585 (Human)

Gene Symbol

GREM1

UniProt

Additional Gremlin Products

Product Documents for Gremlin 1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Gremlin 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Citations for Gremlin 1 Antibody - BSA Free

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Gremlin 1 Antibody - BSA Free

Showing  1 - 2 of 2 FAQs Showing All
  • Q: Are you aware of any references in the published literature which we can use to evaluate the quality of staining?

    A: Unfortunately, this antibody has not yet been used in any publications that we are aware of.

  • Q: Therefore I come to you: firstly, to know whether you tested the antibody for cross-reaction between the two Gremlin isoforms?

    A: The immunogen for NB100-56883 comes from amino acids 52-67 of isoform 1. This sequence is not present in isoform 2 of Gremlin1, so this antibody does not cross-react with isoform 2.

  • Q: Are you aware of any references in the published literature which we can use to evaluate the quality of staining?

    A: Unfortunately, this antibody has not yet been used in any publications that we are aware of.

  • Q: Therefore I come to you: firstly, to know whether you tested the antibody for cross-reaction between the two Gremlin isoforms?

    A: The immunogen for NB100-56883 comes from amino acids 52-67 of isoform 1. This sequence is not present in isoform 2 of Gremlin1, so this antibody does not cross-react with isoform 2.

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