GRK1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-55226

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Monkey

Cited:

Primate - Macaca mulatta (Rhesus Macaque)

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all GRK1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFESVCLEQPIGKKLFQQFLQSA

Reactivity Notes

Use in Monkey reported in scientific literature (PMID:35024589) Mouse 85%, Rat 82%.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GRK1 Antibody - BSA Free

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226] - Staining of human colon, eye, retina, liver and lymph node using Anti-GRK1 antibody NBP2-55226 (A) shows similar protein distribution across tissues to independent antibody NBP2-55732 (B).
Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226] - Staining of human eye, retina.
Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226] - Staining of human lymph node.
Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226] - Staining of human liver.
Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226]

Immunohistochemistry-Paraffin: GRK1 Antibody [NBP2-55226] - Staining of human colon.

Applications for GRK1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Frozen

Reported in scientific literature (PMID:35024589)

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRK1

The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events.

Long Name

G protein-coupled Receptor Kinase 1

Alternate Names

GPRK1, RHOK

Gene Symbol

GRK1

Additional GRK1 Products

Product Documents for GRK1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for GRK1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Intracellular Kinases

Citations for GRK1 Antibody - BSA Free

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Protocols

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FAQs

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