Mouse GSTA1 ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) CV% 6.5 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 10.9 (example only; lot dependent)

Recovery for Mouse GSTA1 ELISA Kit (Colorimetric)

Scientific Data Images for Mouse GSTA1 ELISA Kit (Colorimetric)

Preparation and Storage

Background: GSTA1

GSTA1 is glutathione S-transferase which are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Additional GSTA1 Products

• All Products for GSTA1
• GSTA1 ELISA Kits
• GSTA1 Lysates
• GSTA1 Primary Antibodies
• GSTA1 Proteins and Enzymes

Product Documents for Mouse GSTA1 ELISA Kit (Colorimetric)