Protein kinase inhibitor. IC50
values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C.
Hidaka et al.
The structure and biological activities of the widely used protein kinase inhibitor, H7, differ depending on the commercial source.
Quick et al.
Effect of the kinase inhibitor, H-7, on stress, crossbridge phosphorylation, muscle shortening and inositol phosphate production in rabbit arteries.
Ratz et al.
The citations listed below are publications that use Tocris products. Selected citations for H-7 dihydrochloride include:
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