H-7 dihydrochloride

Catalog # Availability Size / Price Qty
H-7 dihydrochloride | CAS No. 108930-17-2 | Broad Spectrum Protein Kinase Inhibitors
1 Image
Description: Protein kinase inhibitor

Chemical Name: (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride

Purity: ≥99%

Product Details
Citations (4)

Biological Activity

H-7 dihydrochloride is a protein kinase inhibitor (IC50 values for inhibition of PKA, PKG, PKC and myosin light chain kinase are 3.0, 5.8, 6.0 and 97.0 μM, respectively. H-7 shows antiviral activity against influenza A (IC50 = 10 μM) in vitro. H-7 also inhibits interleukin-stimulated secretion of IgM and blocks PMA-stimulated interleukin 1β production.

Technical Data

Soluble to 100 mM in water and to 20 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for H-7 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for H-7 dihydrochloride include:

4 Citations: Showing 1 - 4


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for H-7 dihydrochloride

There are currently no reviews for this product. Be the first to review H-7 dihydrochloride and earn rewards!

Have you used H-7 dihydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.