Hepassocin, also known as fibrinogen like 1 (FGL1) and hepatocyte-derived fibrinogen-related protein 1 (HFREP1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. Hepassocin/FGL1 may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin/FGL1 is upregulated during liver regeneration following partial hepatectomy.
Hepassocin/FGL1 Antibody (160916) [DyLight 488]
Novus Biologicals | Catalog # FAB1105K
Key Product Details
Species Reactivity
Rat
Applications
Western Blot
Label
DyLight 488 (Excitation = 493 nm, Emission = 518 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 160916
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Hepassocin/FGL1
Asp25-Val314
Accession # Q5M8C6
Asp25-Val314
Accession # Q5M8C6
Specificity
Detects rat Hepassocin/FGL1 in direct ELISAs and Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Hepassocin/FGL1 Antibody (160916) [DyLight 488]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Hepassocin/FGL1
Long Name
Fibrinogen Like 1
Alternate Names
FGL1, Fibrinogen-like-protein 1, FREP1
Gene Symbol
FGL1
Additional Hepassocin/FGL1 Products
Product Documents for Hepassocin/FGL1 Antibody (160916) [DyLight 488]
Product Specific Notices for Hepassocin/FGL1 Antibody (160916) [DyLight 488]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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