Key Product Details

Species Reactivity

Human, Mouse, Rat, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

8 GDAAELRkSLkPLLEkRR 25

Reactivity Notes

Chimpanzee

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for HES2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HES2

Transcription factor HES-2, of the HES family of proteins, contains one basic helix-loop-helix (bHLH) domain and one orange domain. It is reported to express in vascular smooth muscle cells, and may have some role in their differentiation. Activation of Notch signaling pathway leads to activation of Hes family genes through the interaction between Notch intracellular domain and RBPSUH (CSL). Hes family proteins are mammalian homologs of Drosophila Hairy and Enhancer of split. The Hes family of transcriptional repressors are implicated in the cell fate determination of stem cells (or precursor cells) by suppressing the expression of tissue-specific transcriptional activators.

Alternate Names

BHLHB40, bHLHb40Class B basic helix-loop-helix protein 40, Hairy and enhancer of split 2, hairy and enhancer of split 2 (Drosophila), transcription factor HES-2

Gene Symbol

HES2

Additional HES2 Products

Product Documents for HES2 Antibody

Certificate of Analysis

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Product Specific Notices for HES2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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