HLA A Antibody Pair

Name: HLA A Antibody Pair
Brand: Novus Biologicals
SKU: H00003105-AP21
Price: 919 USD
Availability: InStock

Novus Biologicals | Catalog # H00003105-AP21

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Product Specifications
Scientific Data
Kit Contents
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Assay Type

Sandwich ELISA

Assay Range

3 ng/ml to 100 ng/ml

Reactivity

Human

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Product Specifications

Description

Quality control test: Standard curve using recombinant protein (H00003105-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human HLA-A.

Conjugate

Unconjugated

Application Notes

Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.

Scientific Data Images for HLA A Antibody Pair

Sandwich ELISA: HLA A Antibody Pair [H00003105-AP21] - Detection sensitivity ranging from 3 ng/ml to 100 ng/ml.

Kit Contents for HLA A Antibody Pair

Capture antibody: rabbit MaxPab affinity purified polyclonal anti-HLA-A (100 ug)
Detection antibody: mouse purified polyclonal anti-HLA-A (20 ug)

Preparation and Storage

Formulation

1x PBS, pH 7.4

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: HLA A

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq]

Alternate Names

A-10 alpha chain, FLJ26655, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-28 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, HLAA, major histocompatibility complex, class I, A, MHC class I antigen A*1, MHC class I antigen A*11, MHC class I antigen A*80

Gene Symbol

HLA-A

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Product Documents for HLA A Antibody Pair

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Certificate of Analysis

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Product Specific Notices for HLA A Antibody Pair

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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