hnRNP-Q Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-29521

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all hnRNP-Q Primary Antibodies »

Product Specifications

Immunogen

between 573 and 623

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for hnRNP-Q Antibody - BSA Free

hnRNP-Q Antibody

Immunoprecipitation:hnRNP-Q AntibodyNBP3-29521] -

Immunoprecipitation:hnRNP-Q AntibodyNBP3-29521] -Detection of human HNRNPQ/R by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from HEK293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-HNRNPQ/R antibody (NBP3-29521 lot 1) used for IP at 2 µg per reaction. For blotting immunoprecipitated HNRNPQ/R, NBP3-29521 was used at 0.1 mg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for hnRNP-Q Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate pH 7 -8.

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: hnRNP-Q

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins

Alternate Names

dJ3J17.2, Glycine- and tyrosine-rich RNA-binding protein, GRYRBP, GRY-RBPNS1-associated protein 1, heterogeneous nuclear ribonucleoprotein Q, hnRNP Q, hnRNP-Q, HNRPQ, HNRPQ1, NSAP1FLJ31626, PP68, synaptotagmin binding, cytoplasmic RNA interacting protein, Synaptotagmin-binding, cytoplasmic RNA-interacting protein

Gene Symbol

SYNCRIP

Additional hnRNP-Q Products

Product Documents for hnRNP-Q Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for hnRNP-Q Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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