HO-1/HMOX1/HSP32 Antibody (CL11669) - BSA Free

Novus Biologicals | Catalog # NBP3-15122

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11669

Format

BSA Free
View all HO-1/HMOX1/HSP32 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P09601, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HO-1/HMOX1/HSP32 Antibody (CL11669) - BSA Free

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11661) [NBP3-15122] - Staining of human spleen shows strong granular cytoplasmic positivity in cells in red pulp.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11661) [NBP3-15122] - Staining of human fallopian tube shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11661) [NBP3-15122] - Staining of human prostate shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11661) [NBP3-15122] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11669) [NBP3-15122]

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody (CL11661) [NBP3-15122] - Analysis in human spleen and skeletal muscle tissues using NBP3-15122 antibody. Corresponding HMOX1 RNA-seq data are presented for the same tissues.

Applications for HO-1/HMOX1/HSP32 Antibody (CL11669) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500-1:1000

Immunohistochemistry-Paraffin

1:500-1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HO-1/HMOX1/HSP32

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Long Name

Heme Oxygenase 1

Alternate Names

HMOX1, HO1, HSP32

Gene Symbol

HMOX1

Additional HO-1/HMOX1/HSP32 Products

Product Documents for HO-1/HMOX1/HSP32 Antibody (CL11669) - BSA Free

Certificate of Analysis

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Product Specific Notices for HO-1/HMOX1/HSP32 Antibody (CL11669) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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