HspA6 Antibody (165f) - BSA Free

Novus Biologicals | Catalog # NBP1-97466

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 165f

Format

BSA Free
View all HSPA6/HSP70B Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to the sequence near the C-terminus of human HspA6 Antibody (165f).

Reactivity Notes

Recognizes Human HSP70B'.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HspA6 Antibody (165f) - BSA Free

Western Blot: HspA6 Antibody (165f) [NBP1-97466]

Western Blot: HspA6 Antibody (165f) [NBP1-97466]

Western Blot: HSPA6 Antibody (165f) [NBP1-97466] - Lane 1: MW marker, Lane 2: HSP70B' Recombinant Protein, Lane 3: HeLa Cell Lysate (Heat Shocked).

Applications for HspA6 Antibody (165f) - BSA Free

Application
Recommended Usage

Western Blot

1:1000
Application Notes
This antibody is useful in Western Blot (Detects a band of ~70kDa).

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.2) and 50% Glycerol

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HSPA6/HSP70B

The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

Long Name

Heat Shock Protein A6

Alternate Names

HSP70B

Gene Symbol

HSPA6

Additional HSPA6/HSP70B Products

Product Documents for HspA6 Antibody (165f) - BSA Free

Certificate of Analysis

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Product Specific Notices for HspA6 Antibody (165f) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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