Home / 5-HT1B / Human 5-HT1B Alexa Fluor® 594-conjugated Antibody

Human 5-HT1B Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB5858T Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB5858T-100UG

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Human 5-HT1B Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human 5HT1B.
Source
Monoclonal Mouse IgG1 Clone # 499325
Purification
Protein A or G purified
Immunogen
NS0 mouse myeloma cell line transfected with human 5HT1B
Met1-Ser390
Accession # P28222
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: 5-HT1B

5HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythm light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches. Human 5HT1B shares 92% aa sequence identity with mouse and rat 5HT1B.

Long Name
5-Hydroxytryptamine Receptor 1B
Entrez Gene IDs
3351 (Human); 15551 (Mouse); 25075 (Rat)
Alternate Names
5HT1B; 5-HT1B; 5-HT1B5-HT-1B; 5HT1DB; 5-HT1DB; 5-hydroxytryptamine (serotonin) receptor 1B; HTR1B; HTR1D2; HTR1D2,5-hydroxytryptamine receptor 1B; HTR1DB; S12; S125-HT-1D-beta; Serotonin 1D beta receptor; Serotonin receptor 1B

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