Human ABCB5 (NP_848654) VersaClone cDNA

Name: Human ABCB5 (NP_848654) VersaClone cDNA
Brand: R&D Systems
SKU: RDC0843
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC0843

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Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_848654

Background: ABCB5

ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 5

Alternate Names

ABCB5 P-gp, ABCB5alpha, ABCB5beta, ATP-binding cassette protein, ATP-binding cassette sub-family B member 5, ATP-binding cassette, sub-family B (MDR/TAP), member 5, EC 3.6.3, EC 3.6.3.44, EST422562, P-glycoprotein ABCB5

Entrez Gene IDs

340273 (Human); 77706 (Mouse); 314537 (Rat)

Gene Symbol

ABCB5

UniProt

NP_848654

Additional ABCB5 Products

Product Documents for Human ABCB5 (NP_848654) VersaClone cDNA

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Product Specific Notices for Human ABCB5 (NP_848654) VersaClone cDNA

For research use only

Related Research Areas

Cancer Biomarkers

Cancer Stem Cell Markers

Obesity

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