Human ACE/CD143 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB9291V Datasheet / COA / SDS

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FAB9291V-100UG

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All ACE/CD143 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ACE/CD143 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects recombinant human (rh)ACE in direct ELISAs and Western blots. Does not cross-react with rhACE-2 or rhNeprilysin.

Source

Monoclonal Mouse IgG1 Clone # 171409

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human ACE
Leu30-Leu1261
Accession # P12821.1

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ACE/CD143

ACE, also known as kininase II and CD143 antigen, is a dipeptidyl carboxyl peptidase that contains zinc. It plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II, a potent vasopressor and aldosterone-stimulating peptide.

Long Name

Angiotensin I Converting Enzyme

Entrez Gene IDs

1636 (Human); 11421 (Mouse)

Alternate Names

ACE; ACE1angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; carboxycathepsin; CD143 antigen; CD143; DCP; DCP1; DCP1angiotensin-converting enzyme; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase I; EC 3.2.1.-; EC 3.4.15.1; Kininase II; MGC26566; MVCD3; peptidase P; testicular ECA