Human alpha -Defensin 5 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB102481N Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB102481N-100UG

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Human alpha -Defensin 5 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human alpha -Defensin 5 in direct ELISAs.
Source
Monoclonal Mouse IgG1 Clone # 972217
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human α-Defensin 5
Thr64-Arg94
Accession # Q01523
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
ELISA
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: alpha-Defensin 5

Defensin alpha 5 (DEFA5), also known as human alpha defensin 5 (HD5), is a secreted antimicrobial protein encoded by the DEFA5 gene and a member of the Defensins family. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA5 is expressed in Paneth cells, which are secretory epithelial cells in the small intestine. Unlike other defensins, DEFA5 is stored in secretory vesicles as a propeptide, and is processed into different peptides with different potency and localization.

Long Name
Defensin Alpha 5
Entrez Gene IDs
1670 (Human)
Alternate Names
alpha-Defensin 5; DEF5; DEF5defensin, alpha 5, preproprotein; DEFA5; defensin 5; Defensin alpha 5; Defensin, alpha 5; defensin, alpha 5, Paneth cell-specific; defensin-5; HD-5; MGC129728

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