Human Angiopoietin-like Protein 7/ANGPTL7 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB914G Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB914G-100UG

Save 15% on Select RUO Reagents. See Details.

All Angiopoietin-like Protein 7/ANGPTL7 Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Angiopoietin-like Protein 7/ANGPTL7 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Angiopoietin-like Protein 7/ANGPTL7 in direct ELISAs and Western blots. In Western blots, less than 3% cross-reactivity with recombinant human Angiopoietin-1 is observed.

Source

Monoclonal Mouse IgG1 Clone # 121408

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Angiopoietin-like Protein 7/ANGPTL7
Lys28-Pro346
Accession # O43827

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Angiopoietin-like Protein 7/ANGPTL7

Angiopoietin-like Protein 7 (ANGPTL7), also known as cornea-derived transcript 6 (CDT6), is a secreted 45 kDa protein that contains a coiled-coil domain (aa 30‑110) and a fibrinogen-like domain (aa 113‑334). ANGPTL7 is expressed in the stromal layer of the cornea, and it forms disulfide-linked homotetramers. It contributes to corneal morphogenesis by suppressing angiogenesis and promoting the deposition of extracellular matrix components. ANGPTL7 is up-regulated in glaucoma and accumulates in the aqueous humor. Mature mouse ANGPTL7 shares 88% and 98% sequence identity with human and rat ANGPTL7.

Long Name

Angiopoietin-like Protein 7

Entrez Gene IDs

10218 (Human); 654812 (Mouse); 102127960 (Cynomolgus Monkey); 714204 (Rhesus Macaque)

Alternate Names

angiopoietin-like 7; Angiopoietin-like factor; Angiopoietin-like Protein 7; angiopoietin-related protein 7; ANGPTL7; AngX; CDT6; CDT6angiopoietin-like factor (CDT6); Cornea-derived transcript 6 protein; dJ647M16.1; RP4-647M16.2