B7-H6 is a transmembrane immune regulatory protein that binds to NKp30 expressed on NK cells. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells. The expression of NKp30 ligands on tumor cells correlates with tumor cell sensitivity to NKp30-dependent cell lysis.
Human B7-H6 (NP_001189368) VersaClone cDNA
R&D Systems | Catalog # RDC1085
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: B7-H6
Long Name
B7 Homolog 6
Alternate Names
B7H6, DKFZp686I21167, DKFZp686O24166, NCR3LG1
Gene Symbol
NCR3LG1
UniProt
Additional B7-H6 Products
Product Documents for Human B7-H6 (NP_001189368) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human B7-H6 (NP_001189368) VersaClone cDNA
For research use only
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