Human CD24 Antibody [Biotin]

R&D Systems | Catalog # FAB52471B

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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Biotin

Antibody Source

Polyclonal Sheep IgG
View all CD24 Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human CD24
Ser27-Gly59
Accession # NP_037362

Specificity

Detects human CD24 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Scientific Data Images for Human CD24 Antibody [Biotin]

Detection of CD24 antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

Detection of CD24 in Human Blood Lymphocytes by Flow Cytometry.

Human peripheral blood lymphocytes were stained with either (A) Sheep Anti-Human CD24 Biotinylated Polyclonal Antibody (Catalog # FAB52471B) or (B) Sheep IgG Control Antibody (BAF020) followed by PE-conjugated Streptavidin (F0040) and Mouse Anti-Human CD19 APC-conjugated Monoclonal Antibody (FAB4867A). Staining was performed using our Staining Membrane-associated Proteins protocol.

Applications for Human CD24 Antibody [Biotin]

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human PBMC lymphocytes

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD24

CD24 (signal transducer 24; also HSA/heat shock antigen) is a variably glycosylated, 35‑50 kDa member of the CD24 family of proteins. It is a GPI‑linked sialoprotein that is expressed on B cell precursors and unactivated B cells, keratinocytes, and neutrophils and thymocytes. Ligation of CD24 appears to inhibit B cell differentiation, likely through the initiation of apoptosis. Potential CD24 ligands include P‑Selectin. The human CD24 precursor is 80 amino acids (aa) in length. It contains a 26 aa signal sequence plus a cleavable C‑terminal propeptide (aa 60‑80). There is one potential alternate start site at Met5. Over aa 27‑59, human CD24 shares only 30% aa identity with mouse CD24.

Alternate Names

CD24, CD24A

Entrez Gene IDs

100133941 (Human); 12484 (Mouse)

Gene Symbol

CD24

UniProt

NP_037362

Additional CD24 Products

Product Documents for Human CD24 Antibody [Biotin]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CD24 Antibody [Biotin]

For research use only

Citations for Human CD24 Antibody [Biotin]

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