Human ChemR23 Alexa Fluor® 350-conjugated Antibody

FAB362U Datasheet / COA / SDS

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FAB362U-100UG

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Human ChemR23 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human ChemR23. Stains human ChemR23-transfected cells but not irrelevant transfectants.

Source

Monoclonal Mouse IgG3 Clone # 84939

Immunogen

NS0 mouse myeloma cell line transfected with human ChemR23
Met1-Leu371
Accession # NP_004063

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

0.25-1 µg/10⁶ cells

Human peripheral blood monocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: ChemR23

ChemR23 is a chemoattractant receptor expressed on dendritic cells and activated macrophages. ChemR23 binds Chemerin and functions as a coreceptor for SIV and some primary HIV-1 strains.

References

Samson, M. et al. (1998) Eur. J. Immunol. 28:1689.

Long Name

Chemokine-like Receptor 1/Orphan G Protein-coupled Receptor ChemR23

Entrez Gene IDs

1240 (Human); 14747 (Mouse); 60669 (Rat)

Alternate Names

CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; ChemR23; cmklr1; Dez; Gpcr27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; MGC126105; MGC126106; orphan G-protein coupled receptor, Dez