Human CMG-2/ANTXR2 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB29401T Datasheet / COA / SDS

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FAB29401T-100UG

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All CMG-2/ANTXR2 Antibodies

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Human CMG-2/ANTXR2 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human CMG-2/ANTXR2 in direct ELISAs.

Source

Monoclonal Mouse IgG1 Clone # 406510

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CMG-2/ANTXR2
Ser22-Arg200
Accession # P58335

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

ELISA

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CMG-2/ANTXR2

Capillary Morphogenesis Protein 2 (CMG-2) is an anthrax toxin receptor (ATR) family protein that contains a von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus Anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment of anthrax. Within the region used as immunogen, human and mouse CMG-2 share 76% amino acid sequence homology.

Long Name

Capillary Morphogenesis Protein 2

Entrez Gene IDs

118429 (Human); 71914 (Mouse)

Alternate Names

anthrax toxin receptor 2; ANTXR2; Capillary morphogenesis gene 2 protein; capillary morphogenesis protein 2; cI-35; CMG2; CMG-2; CMG2MGC111533; CMG-2MGC45856; FLJ31074; ISH; JHF; JHS