Human CMG-2/ANTXR2 Antibody (406510)

R&D Systems | Catalog # MAB29401

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 406510
View all CMG-2/ANTXR2 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CMG-2/ANTXR2
Ser22-Arg200
Accession # P58335

Specificity

Detects human CMG-2/ANTXR2 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human CMG-2/ANTXR2 Antibody (406510)

Human CMG-2 DuoSet ELISA Standard Curve

Human CMG-2 DuoSet ELISA Standard Curve

Recombinant Human CMG‑2/ANTXR2 (Catalog # 2940-CM) was serially diluted and captured by Mouse Anti-Human CMG‑2/ANTXR2 Monoclonal Antibody (Catalog # MAB29401) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human CMG‑2/ANTXR2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2940) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)

Applications for Human CMG-2/ANTXR2 Antibody (406510)

Application
Recommended Usage

ELISA

This antibody functions as an ELISA capture antibody when paired with Goat Anti-Human CMG‑2/ANTXR2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2940).

This product is intended for assay development on various assay platforms requiring antibody pairs.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.<br/>*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CMG-2/ANTXR2

Capillary Morphogenesis Protein 2 (CMG-2) is an anthrax toxin receptor (ATR) family protein that contains a von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus Anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment of anthrax. Within the region used as immunogen, human and mouse CMG-2 share 76% amino acid sequence homology.

Long Name

Capillary Morphogenesis Protein 2

Alternate Names

ANTXR2, cI-35, CMG2, ISH, JHS

Entrez Gene IDs

118429 (Human); 71914 (Mouse)

Gene Symbol

ANTXR2

UniProt

P58335

Additional CMG-2/ANTXR2 Products

Product Documents for Human CMG-2/ANTXR2 Antibody (406510)

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CMG-2/ANTXR2 Antibody (406510)

For research use only

Related Research Areas

Infectious Diseases

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