Human CRACC/SLAMF7 Alexa Fluor® 700-conjugated Antibody Summary
Accession # Q9NQ25
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of CRACC/SLAMF7 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon PE‑conjugated Monoclonal Antibody (Catalog # FAB100P) and either (A) Mouse Anti-Human CRACC/SLAMF7 Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB1906N) or (B) Mouse IgG2A Alexa Fluor 700 Isotype Control (Catalog # IC003N). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
CRACC, also known as CSI (CD2 subset I) and CD319, is a type I transmembrane protein belonging to the CD2 subset of the Ig superfamily. CRACC is expressed on most NK cells and subsets of CD8+ cells, CD4+ cells and B cells. CRACC may play a role in the activation and effector function of T cells and NK cells and likely participates in B cell adhesion. Over amino acids (aa) 27-225, human and mouse SLAMF7 share 53% aa sequence identity.
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