Human Creatine Kinase MM/CKMM Alexa Fluor® 594-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB5564T-100UG

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Human Creatine Kinase MM/CKMM Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Creatine Kinase, Muscle/CKMM in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG1 Clone # 492731
Purification
Protein A or G purified
Immunogen
Human cardiac muscle-derived Creatine Kinase, Muscle/CKMM
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Creatine Kinase MM/CKMM

Creatine kinase (CK) is a 40 kDa cytoplasmic enzyme that is integral to energy metabolism in striated muscle through the maintenance of ATP levels. It is a dimeric protein composed of tissue specific M (muscle) and B (brain) subunits. The homodimeric CKMM isozyme is predominantly expressed in differentiated skeletal and cardiac muscle fibers. The M subunit of human creatine kinase shares 97% aa sequence identity with the mouse and rat M subunit and 81% with the human B subunit.

Long Name
Creatine Kinase, Muscle
Entrez Gene IDs
1158 (Human); 12715 (Mouse); 24265 (Rat)
Alternate Names
CKM; CKMM; CKMMcreatine kinase M-type; Creatine Kinase Isoenzyme; Creatine kinase M chain; Creatine Kinase MM; creatine kinase, muscle; creatine kinase-M; EC 2.7.3; EC 2.7.3.2; M-CK

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