Human CREG Alexa Fluor® 700-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2380N-100UG

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Human CREG Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CREG in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CREG is observed.
Source
Monoclonal Mouse IgG2b Clone # 299133
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CREG
Arg32-Gln220
Accession # O75629
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CREG

CREG is a secreted glycoprotein that belongs to the CREG protein family. It is induced during differentiation of pluripotent cells and is ubiquitously expressed in adult tissues. Mannose-6 phosphate (M6P) modified CREG binds directly to the M6P/IGF2 receptor to inhibit cell growth (1). Human and mouse CREG share approximately 77% amino acid sequence homology.

Long Name
Cellular Repressor of E1A-stimulated Genes
Entrez Gene IDs
8804 (Human); 433375 (Mouse)
Alternate Names
cellular repressor of E1A-stimulated genes 1CREG; cellular repressor of E1A-stimulated genes; CREG; CREG1; protein CREG1

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