Human CRISP-2 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB2575S Datasheet / COA / SDS

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FAB2575S-100UG

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Human CRISP-2 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human CRISP-2 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human CRISP-3 is observed.

Source

Monoclonal Mouse IgG2b Clone # 350814

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CRISP-2
Lys22-Tyr243
Accession # P16562

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CRISP-2

Human CRISP-2, the ortholog of rodent testis specific protein 1 (Tpx1) is a secreted protein expressed in testis. It is a cell adhesion molecule that mediates interactions between spermatogenic cells and Sertoli cells. Mature human CRISP-2 shares 86%, 73% and 71% amino acid sequence identity with the equine, mouse and rat proteins, respectively. Human CRISP-2 also shares 71% amino acid sequence homology with human CRISP-3.

Long Name

Cysteine-rich Secretory Protein 2

Entrez Gene IDs

7180 (Human); 22024 (Mouse)

Alternate Names

Cancer/testis antigen 36; CRISP2; CRISP-2; CRISP-2GAPDL5; CT36TSP1; cysteine-rich secretory protein 2; GAPDL5; glyceraldehyde-3-phosphate dehydrogenase-like 5; testis specific protein 1 (probe H4-1 p3-1); Testis-specific protein TPX-1; TPX1; TPX1MGC111136; TSP1