Human DEC-205/CD205 Alexa Fluor® 350-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: DEC-205/CD205

DEC-205, also known as CD205 and lymphocyte antigen 75 (Ly 75), is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. The extracellular region of DEC-205 contains ten C-type lectin-like domains, a fibronectin type II domain and a ricin B-type lectin domain. DEC-205 functions as an endocytic receptor for antigens. The recombinant protein used to generate the anti-human DEC-205 antibody contains the first two C-type lectin domains.

Product Datasheets

Related Research Areas

• Conventional/Classical Dendritic Cells
• C-type Lectin Family
• C-type Lectin Receptors
• Dendritic Cell Pathogen Recognition/Uptake
• Dendritic Cells
• Langerhans and Dermal Dendritic Cells
• Mouse Tissue-Resident Macrophage Markers