Human DEC-205/CD205 Alexa Fluor® 700-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2047N-100UG
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Human DEC-205/CD205 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human DEC‑205/CD205 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse DEC-205 is observed.
Source
Monoclonal Mouse IgG1 Clone # 523203
Immunogen
E. coli-derived recombinant human DEC‑205/CD205
Cys216-Cys501
Accession # O60449
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 700

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human peripheral blood monocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: DEC-205/CD205

DEC-205, also known as CD205 and lymphocyte antigen 75 (Ly 75), is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. The extracellular region of DEC-205 contains ten C-type lectin-like domains, a fibronectin type II domain and a ricin B-type lectin domain. DEC-205 functions as an endocytic receptor for antigens. The recombinant protein used to generate the anti-human DEC-205 antibody contains the first two C-type lectin domains.

Entrez Gene IDs
4065 (Human)
Alternate Names
CD205; DEC205; DEC-205; Ly75

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