Human DLL3 PE‑conjugated Antibody

R&D Systems | Catalog # FAB4315P

R&D Systems

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Polyclonal Goat IgG
View all DLL3 Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human DLL3
Ala27-Pro488
Accession # Q9NYJ7

Specificity

Detects human DLL3 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) DLL1 is observed and less than 8% cross-reactivity with rhDLL4 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human DLL3 PE‑conjugated Antibody

Detection of DLL3 antibody in U-118-MG Human Cell Line antibody by Flow Cytometry.

Detection of DLL3 in U‑118‑MG Human Cell Line by Flow Cytometry.

U-118-MG human glioblastoma/astrocytoma cell line was stained with Goat Anti-Human DLL3 PE-conjugated Polyclonal Antibody (Catalog # FAB4315P, filled histogram) or isotype control antibody (Catalog # IC108P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human DLL3 PE‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: U-118-MG human glioblastoma/astrocytoma cell line

Reviewed Applications

Read 2 reviews rated 5 using FAB4315P in the following applications:

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: DLL3

DLL3 (Delta-like protein 3; also Delta3) is a 65‑67 kDa member of the Delta family of proteins. It is expressed in/on select cell types in the embryo, including somitic mesoderm, cochlear hair cells and noncycling cells of the neural tube that are undergoing differentiation. DLL3 is principally found in the Golgi apparatus and endosomes where it promotes Notch family receptor degradation. Mature human DLL3 is a 592 amino acid (aa) type I transmembrane protein. It possesses a 466 aa extracellular domain (aa 27-492) that contains a Notch-binding DSL domain (aa 176-215) followed by six EGF-like repeats (aa 216-465). There is one isoform variant that contains an Ala substitution for aa 588-618. Over aa 27-488, human DLL3 shares 84% aa identity with mouse DLL3.

Long Name

Delta-like 3

Alternate Names

Pudgy, SCDO1

Entrez Gene IDs

10683 (Human); 13389 (Mouse); 114125 (Rat)

Gene Symbol

DLL3

UniProt

Q9NYJ7 (Human)

Additional DLL3 Products

Product Documents for Human DLL3 PE‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human DLL3 PE‑conjugated Antibody

For research use only

Related Research Areas

Cancer Biomarkers
Notch Pathway

Citations for Human DLL3 PE‑conjugated Antibody

Customer Reviews for Human DLL3 PE‑conjugated Antibody (2)

5 out of 5
2 Customer Ratings
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

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Customer Images

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  • Human DLL3 PE-conjugated Antibody
    Name: Cristiano Fieni
    Application: Flow Cytometry
    Sample Tested: DU145 human prostate carcinoma cell line
    Species: Human
    Verified Customer | Posted 11/21/2025
    Human DLL3 PE‑conjugated Antibody FAB4315P
  • Human DLL3 PE-conjugated Antibody
    Name: Anonymous
    Application: Flow Cytometry
    Sample Tested: Cancer Tissue
    Species: Human
    Verified Customer | Posted 11/01/2021
    Detection of DLL3 on CD45- cells from a Non-Small Cell Lung Cancer patient tissue. Single-cell suspension was generated from a lung cancer tissue biopsy and cells were treated a CD45 antibody along with the goat polyclonal Human DLL3 PE-conjugated Antibody (catalog # FAB4315P) (BLUE) or Goat IgG PE-conjugated Antibody (catalog # IC108P) (RED).
    Human DLL3 PE‑conjugated Antibody FAB4315P

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FAQs

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail