Human DNA-PKcs Alexa Fluor® 750-conjugated Antibody

Catalog #: AF3415S Datasheet / COA / SDS

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AF3415S-100UG

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All DNA-PKcs Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human DNA-PKcs Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human DNA-PK_CSin Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human DNA-PK_CS
Thr3844-Trp4127
Accession # P78527

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DNA-PKcs

DNA-dependent protein kinase catalytic subunit (DNA-PK_CS) is a member of the PI3-kinase related kinase (PIKK) superfamily. DNA-PK_CS is a serine/threonine kinase that, along with the DNA-binding proteins Ku70/Ku80, binds to regions of DNA double-strand breaks and is involved in double-strand break repair and VDJ recombination.

Long Name

DNA-dependent Protein Kinase Catalytic Subunit

Entrez Gene IDs

5591 (Human); 19090 (Mouse); 360748 (Rat)

Alternate Names

DNA-dependent protein kinase catalytic subunit-like; DNA-dependent protein kinase; DNA-PK catalytic subunit; DNAPK; DNAPKcs; DNA-PKcs; DNPK1; EC 2.7.11.1; HYRC; HYRC1; p350; p460; PRKDC; XRCC7