Human DPEP1 (NP_004404.1) VersaClone cDNA

R&D Systems | Catalog # RDC3188

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: DPEP1

DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renalmetabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 (PubMed 6122685)). DPEP1 isresponsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984(PubMed 6334084)). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probablefunction was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibitselective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 (PubMed2303490)).(supplied by OMIM)

Long Name

Dipeptidase 1

Alternate Names

HRDP, Microsomal Dipeptidase, Renal Dipeptidase

Entrez Gene IDs

1800 (Human)

Gene Symbol

DPEP1

UniProt

Additional DPEP1 Products

Product Documents for Human DPEP1 (NP_004404.1) VersaClone cDNA

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human DPEP1 (NP_004404.1) VersaClone cDNA

For research use only

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