Human Enteropeptidase/Enterokinase Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB1585R Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB1585R-100UG

Save 15% on Select RUO Reagents. See Details.

All Enteropeptidase/Enterokinase Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Enteropeptidase/Enterokinase Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Enteropeptidase/Enterokinase in direct ELISAs and Western blots. It recognizes all EK forms containing the heavy chain including the single chain precursor and the mature heterodimer consisting of a heavy and light chain. In Wester

Source

Monoclonal Mouse IgG2a Clone # 190034

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Enteropeptidase/Enterokinase
Leu41-His1019
Accession # NP_002763

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Enteropeptidase/Enterokinase

Enterokinase (EK), also called enteropeptidase and TMPRSS15 (gene name), initiates activation of pancreatic proteases by converting trypsinogen to trypsin, which in turn activates chymotrypsin, carboxypeptidases and elastases. Located in intestinal brush border, it is a disulfide bond-linked dimer of the heavy and light chains, which are derived from the same single-chain precursor. The heavy chain consists of a short cytoplamic tail, a transmembrane, a SEA, a SRCR, a MAM, two CUB and two LDL-receptor class A domains. The light chain contains the catalytic domain of trypsin-like serine proteases.

Entrez Gene IDs

5651 (Human)

Alternate Names

EC 3.4.21; EC 3.4.21.9; Enterokinase; Enteropeptidase; ENTK; ENTKenterokinase; MGC133046; protease, serine, 7 (enterokinase); PRSS7; PRSS7enteropeptidase; Serine protease 7; TMPRSS15; Transmembrane protease serine 15; transmembrane protease, serine 15