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Expression of the fatty acyl-CoA synthetase ACSVL3, also known as FATP3, was found to be markedly elevated in clinical malignant glioma specimens but nearly undetectable in normal glia. FATP3 expression was induced by the activation of oncogenic receptor tyrosine kinases (RTK) c-Met and epidermal growth factor receptor. FATP3 maintains oncogenic properties of malignant glioma cells via a mechanism that involves the regulation of Akt function.
Fatty Acid Transport Protein 3
Entrez Gene IDs:
11000 (Human); 26568 (Mouse)
ACSVL3; EC 6.2.1; EC 6.2.1.-; EC 18.104.22.168; FATP3; FATP-3; FATP3ACSVL3MGC4365; Fatty acid transport protein 3; long-chain fatty acid transport protein 3; SLC27A3; solute carrier family 27 (fatty acid transporter), member 3; Solute carrier family 27 member 3; Very long-chain acyl-CoA synthetase homolog 3; VLCS-3
Have you used Human FATP3 (NP_077306) VersaClone cDNA?
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