Human GLRA1 (NP_001139512) VersaClone cDNA

Name: Human GLRA1 (NP_001139512) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2911
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC2911

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_001139512

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GLRA1

Glycine is an important inhibitory neurotransmitter in the mammalian central nervous system, especially in the brainstem and spinal cord. It acts by binding to anion-conducting glycine receptors that belong to a superfamily of ligand-gated ion channels. Glycine receptors were first purified as strychnine binding sites in membrane fractions of adult spinal cord from rats (1). These strychnine-sensitive binding sites are different from the strychnine-insensitive binding sites found in the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors. Adult glycine receptors are heterodimers composed of two subunits of 48 kDa and 58 kDa, denoted as a1 and b subunits. Fetal glycine receptors are homomers composed of a2 subunits.

Long Name

Glycine Receptor alpha 1

Alternate Names

HKPX1

Entrez Gene IDs

2741 (Human); 14654 (Mouse)

Gene Symbol

GLRA1

UniProt

NP_001139512

Additional GLRA1 Products

Product Documents for Human GLRA1 (NP_001139512) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human GLRA1 (NP_001139512) VersaClone cDNA

For research use only

Related Research Areas

Neurotransmitter Receptors, Transporters, and Ion Channels

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