Human GluR7/GRIK3 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB11328X Datasheet / COA / SDS

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FAB11328X-100UG

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All GluR7/GRIK3 Antibodies

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Human GluR7/GRIK3 Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human GluR7/GRIK3 in direct ELISA.

Source

Monoclonal Mouse IgG2b Clone # 1059901

Purification

Protein A or G purified

Immunogen

Human GluR7/GRIK3 containing peptide.
Accession # Q13003

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GluR7/GRIK3

GluR7 is a receptor for glutamate. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain. This gene can co-assemble with GRIK4 or GRIK5 to form heteromeric receptors. GluR7 is one of the five subtypes of kainate receptors. Kainate receptors are widely expressed in the CNS and are involved in the regulation of transmitter release, synapse formation, and in the pathophysiology of brain diseases. Genetic variants in the GluR7 gene are associated with schizophrenia, major depression, and bipolar disorder.

Long Name

Glutamate Receptor 7

Entrez Gene IDs

2899 (Human); 14807 (Mouse); 298521 (Rat)

Alternate Names

EAA5; Excitatory amino acid receptor 5; GLR7; GluK3; GluR7; gluR-7; GluR7a; GLUR7dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); Glutamate receptor 7; glutamate receptor, ionotropic kainate 3; glutamate receptor, ionotropic, kainate 3; GRIK3