Human GPR37 (NP_005293) VersaClone cDNA

Name: Human GPR37 (NP_005293) VersaClone cDNA
Brand: R&D Systems
SKU: RDC0066
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC0066

Submit a review

Product Documents

100% Guarantee

Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_005293

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GPR37

GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death. GPR37 expression has been reported in brain, liver, and placenta. ESTs have been isolated from brain, embryo, eye, fetal lung/testis/Bcell, gallbladder, heart, liver, liver/spleen, melanocyte/uterus/fetal heart, nerve, placenta, testis, tonsil, and vessel libraries.

Long Name

G Protein-coupled Receptor 37

Alternate Names

ETBR-LP-1, PAELR

Entrez Gene IDs

2861 (Human); 14763 (Mouse); 117549 (Rat)

Gene Symbol

GPR37

UniProt

NP_005293

Additional GPR37 Products

Product Documents for Human GPR37 (NP_005293) VersaClone cDNA

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human GPR37 (NP_005293) VersaClone cDNA

For research use only

Customer Reviews for Human GPR37 (NP_005293) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human GPR37 (NP_005293) VersaClone cDNA and earn rewards!

Have you used Human GPR37 (NP_005293) VersaClone cDNA?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image