Human Hepassocin/FGL1 (NP_004458) VersaClone cDNA Summary
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Hepassocin, also known as fibrinogen like 1 (FGL1) and hepatocyte-derived fibrinogen-related protein 1 (HFREP1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. Hepassocin/FGL1 may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin/FGL1 is upregulated during liver regeneration following partial hepatectomy.
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