Indoleamine 2,3-dioxygenase (IDO) is a heme-containing intracellular dioxygenase catalyzing the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine. IDO is widely expressed in dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. In immune cells, its expression is mainly induced by cytokines such as IFN gamma, IFN alpha, IFN beta, and IL-10. IDO has an antimicrobial function and induces immunosuppression during infection, pregnancy, transplantation, autoimmunity, and neoplasia.
Human IDO (NP_002155) VersaClone cDNA
R&D Systems | Catalog # RDC1995
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Indoleamine 2,3-dioxygenase/IDO
Alternate Names
3dioxygenase, IDO, IDO1, INDO, Indoleamine 2
Gene Symbol
IDO1
UniProt
Additional Indoleamine 2,3-dioxygenase/IDO Products
Product Documents for Human IDO (NP_002155) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human IDO (NP_002155) VersaClone cDNA
For research use only
Related Research Areas
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