Human IFN-alpha 6/IFNA6 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB10212N Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB10212N-100UG

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Human IFN-alpha 6/IFNA6 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human IFN-alpha 6/IFNA6 in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG2a Clone # 1009720
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human IFN-alpha 6/IFNA6
Leu28-Lys207
Accession # Q90W0
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IFN-alpha 6/IFNA6

Interferon kappa, also known as IFN-kappa, is a 207 aminoacids protein that in humans is encoded by the IFNK gene. IFN-kappa is a member of the type I interferon family which also includes IFN-alpha, -beta, -epsilon, and -omega. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. Human IFN-kappa has been detected in keratinocytes, monocytes, and monocyte-derived dendritic cells and is reported to have contact-dependent antiviral activity. Human papillomavirus (HPV) 16 oncogene expression, which is necessary for the development of cervical cancer, has been shown to down-regulate human IFN-kappa expression.

Long Name
Interferon alpha 6
Entrez Gene IDs
3443 (Human); 15969 (Mouse)
Alternate Names
IFNA6; IFN-alpha 6; IFNalpha K; IFN-alpha K; IFN-kappa; interferon kappa; interferon, kappa; RP11-27J8.1; UNQ6124/PRO20084

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