Human IFN-beta Antibody

Catalog # Availability Size / Price Qty
31410-1
Product Details
Citations (2)
FAQs
Reviews

Human IFN-beta Antibody Summary

Species Reactivity
Human
Specificity
Detects Human IFN‑ beta
Source
Polyclonal Rabbit Serum
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human IFN-beta
Formulation
Serum.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Neutralization

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, this product should be kept at -70 ˚C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed – the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

Background: IFN-beta

Interferon-beta (IFN-beta), along with IFN-alpha and IFN-omega, is a member of the type I interferon family. All three type I interferons share a common cell surface receptor that is composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. Type I interferons were originally described as potent anti-viral molecules produced by virally infected cells.

Long Name
Interferon beta
Entrez Gene IDs
3456 (Human); 15977 (Mouse); 24481 (Rat)
Alternate Names
Fibroblast interferon; IFBIFNB; IFF; IFNB1; IFNbeta; IFN-beta; interferon beta; interferon, beta 1, fibroblast; MGC96956

Product Datasheets

Citations for Human IFN-beta Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Uterine epithelial cells specifically induce interferon-stimulated genes in response to polyinosinic-polycytidylic acid independently of estradiol.
    Authors: Patel MV, Ghosh M, Fahey JV, Wira CR
    PLoS ONE, 2012;7(4):e35654.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  2. The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3.
    Authors: Lee SH, Kim JS, Jun HK
    J. Immunol., 2009;182(9):5823-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization

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