Interleukin 34 (IL-34) is secreted as a homodimer consisting of 39 kDa monomers. It belongs to no known cytokine family. The mature chain contains one potential site for N-linked glycosylation. IL-34 is widely expressed, but it is most abundant in the spleen. The receptor for IL-34 is colony-stimulating factor 1 receptor (CSF-1R). Functionally, IL-34 stimulates monocyte viability.
Human IL‑34 Biotinylated Antibody
R&D Systems | Catalog # BAM52652
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Key Product Details
Species Reactivity
Human
Applications
ELISA Detection (Matched Antibody Pair)
Label
Biotin
Antibody Source
Monoclonal Mouse IgG1 Clone # 578401
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL-34
Asn21-Pro242
Accession # NP_689669
Asn21-Pro242
Accession # NP_689669
Specificity
Detects human IL-34 in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse IL-34 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human IL‑34 Biotinylated Antibody
Human IL-34 Sandwich Immunoassay
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: IL-34
Long Name
Interleukin 34
Alternate Names
C16orf77, IL34
Gene Symbol
IL34
UniProt
Additional IL-34 Products
Product Documents for Human IL‑34 Biotinylated Antibody
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human IL‑34 Biotinylated Antibody
For research use only
Related Research Areas
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