Human Integrin alpha 4/CD49d Alexa Fluor® 350-conjugated Antibody

Catalog #: BBA37U Datasheet / COA / SDS

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BBA37U-100UG

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Human Integrin alpha 4/CD49d Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Integrin alpha 4 subunit (Needham, L.A. et al. (1994) Cell Adhesion and Communication 2:87).

Source

Monoclonal Mouse IgG1 Clone # 2B4

Purification

Protein A or G purified

Immunogen

U937 human histiocytic lymphoma cell line

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Adhesion Blockade

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Integrin alpha 4/CD49d

Integrin alpha 4, also known as CD49d, is a transmembrane protein that forms heterodimers with beta 1 or beta 7 integrins. These complexes contribute to the trafficking of many hematopoietic cell types. Integrins alpha 4 beta 1 (also known as VLA-4) and alpha 4 beta 7 (LPAM-1) are receptors for fibronectin, VCAM and MAdCAM-1.

Entrez Gene IDs

3676 (Human); 16401 (Mouse); 102128433 (Cynomolgus Monkey)

Alternate Names

269C wild type; CD49 antigen-like family member D; CD49d antigen; CD49d; CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor; IA4; Integrin alpha 4; integrin alpha-4 subunit; integrin alpha-4; Integrin alpha-IV; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); ITGA4; MGC90518; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha; VLA-4