IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.
Human IRAK1 (AAH54000.1) VersaClone cDNA
R&D Systems | Catalog # RDC3699
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IRAK1
Long Name
Interleukin-1 Receptor-Associated Kinase 1
Alternate Names
Il1rak, Pelle, Plpk
Gene Symbol
IRAK1
UniProt
Additional IRAK1 Products
Product Documents for Human IRAK1 (AAH54000.1) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human IRAK1 (AAH54000.1) VersaClone cDNA
For research use only
Related Research Areas
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