Human IRAK1 (NP_001560.2) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC3587
R&D Systems VersaClone cDNA Plasmids
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Human IRAK1 (NP_001560.2) VersaClone cDNA Summary

Specifications

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: IRAK1

IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.

Long Name
Interleukin-1 Receptor-Associated Kinase 1
Entrez Gene IDs
3654 (Human); 16179 (Mouse); 363520 (Rat)
Alternate Names
EC 2.7.11; EC 2.7.11.1; Il1rak; interleukin-1 receptor-associated kinase 1; IRAK1; IRAK-1; IRAKPelle homolog; Pelle; Plpk

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