Detection of KIR2DS5/CD158g in BaF3 Mouse Cell Line Transfected with KIR2DS5/CD158g by Flow Cytometry.
BaF3 mouse pro-B cell line transfected with KIR2DS5/CD158g were stained with Rabbit Anti-Human KIR2DS5/CD158g Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB8920R, filled histogram) or control antibody Rabbit Anti-Human KIR3DL3/CD158z Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB8919R, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Killer-immunoglobulin-like receptors (KIR) are polymorphous activating and inhibitory receptors expressed on the surface of NK cells and some T cells. KIR genes are highly homologous. KIR proteins expressing the long (L) cytoplasmic domain are inhibitory, while KIRs with short (S) cytoplasmic domains are activating. Thus, KIR2DS5 is a 65 kDa type I transmembrane activating receptor for NK cells, and is thought to play a role in NK cell function in response to a number of conditions. While many KIR proteins bind HLA-class I molecules, the ligand(s) for KIR2DS5 remain unclear.
Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 5
Entrez Gene IDs:
killer cell immunoglobulin-like receptor 2DS5; CD158g; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5; KIR2DS5; NKAT9
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