Human KIR3DS1/CD158e2 (Q14943) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0519
R&D Systems VersaClone cDNA Plasmids
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Human KIR3DS1/CD158e2 (Q14943) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: KIR3DS1/CD158e2

The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.

Long Name
Killer Cell Immunoglobulin-like Receptor, Three Domains, Long Cytoplasmic Tail, 1
Entrez Gene IDs
3813 (Human)
Alternate Names
CD158e2; KIR3DS1; KIR-G1; nkat10

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