Human Lgr6 (NP_001017403) VersaClone cDNA Summary
Lgr6 is a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. Lgr6 is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. In humans, Lgr6 is phosphorylated upon DNA damage, probably by ATM or ATR.
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