Leukocyte Immunoglobulin-like Receptor 6 (LIR-6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged amino acid (aa) within the TM domain which interacts with FcR gamma. Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR-6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity.
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Pro17-Asn461
Accession # O75019
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human LILRA1/LILRB1 APC‑conjugated Antibody
Detection of LILRA1/LILRB1 in Human Blood Monocytes by Flow Cytometry.
Human peripheral blood monocytes were stained with Mouse Anti-Human LILRA1/LILRB1 APC-conjugated Monoclonal Antibody (Catalog # FAB30851A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Applications for Human LILRA1/LILRB1 APC‑conjugated Antibody
Flow Cytometry
Sample: Human peripheral blood monocytes
Reviewed Applications
Read 1 review rated 5 using FAB30851A in the following applications:
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Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: LILRA1/LILRB1
Long Name
Alternate Names
UniProt
Additional LILRA1/LILRB1 Products
Product Documents for Human LILRA1/LILRB1 APC‑conjugated Antibody
Certificate of Analysis
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Product Specific Notices for Human LILRA1/LILRB1 APC‑conjugated Antibody
For research use only
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Application: Flow CytometrySample Tested: Peripheral blood mononuclear cells (PBMCs)Species: HumanVerified Customer | Posted 06/24/2018
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Protocols
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