LILRA4, also known as ILT7 and CD85g, is a transmembrane immunoregulatory protein that is expressed on plasmacytoid dendritic cells (pDC) but is downregulated in response to TLR9 signaling. It associates with Fc epsilon RI gamma, and this complex binds to cell surface BST2/Tetherin on monocytes, plasmacytoid and myeloid dendritic cells, B cells, and activated CD4+ and CD8+ T cells. This interaction inhibits the TLR7 and TLR9 induced pDC production of type I interferons, IL-6, and TNF-alpha.
Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
R&D Systems | Catalog # RDC1081
Loading...
Loading...
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: LILRA4/CD85g/ILT7
Long Name
Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 4
Alternate Names
CD85g, ILT7
Entrez Gene IDs
23547 (Human)
Gene Symbol
LILRA4
UniProt
Additional LILRA4/CD85g/ILT7 Products
Product Documents for Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
For research use only
Customer Reviews for Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA and earn rewards!
Have you used Human LILRA4/CD85g/ILT7 (NP_036408) VersaClone cDNA?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review