Lectin-like Oxidized Low-density Lipoprotein Receptor 1 (LOX-1), also known as Oxidized Low-density Lipoprotein Receptor 1 (OLR1), is a type II transmembrane receptor belonging to the class E scavenger receptor (SR-E) subfamily of the C-type lectin family. It binds and supports the internalization of multiple structurally unrelated macromolecules. It exists on the cell surface as covalent homodimers, which can further associate into non-covalently-linked oligomers. Cell surface LOX-1 can also be cleaved to release the soluble LOX-1 extracellular domain.
Human LOX-1/OLR1 (NP_002534) VersaClone cDNA
R&D Systems | Catalog # RDC1650
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Background: LOX-1/OLR1
Long Name
Lectin-like Oxidized Low-density Lipoprotein Receptor 1
Alternate Names
CLEC8A, LOX1, OLR1, SCARE1, SR-E1
Gene Symbol
OLR1
UniProt
Additional LOX-1/OLR1 Products
Product Documents for Human LOX-1/OLR1 (NP_002534) VersaClone cDNA
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Product Specific Notices for Human LOX-1/OLR1 (NP_002534) VersaClone cDNA
For research use only
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